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KMID : 1103720090600030165
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Journal of the Korean Society of Radiology
2009 Volume.60 No. 3 p.165 ~ p.172
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Comparison of CT or MRI and 18F-FDG PET/CT for the Preoperative Staging Accuracy of Ovarian Cancer
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Lee Young-Joon
Yoo Ie-Ryung
Chung Soo-Kyo
Jung Guk-Won
Oh Soon-Nam
Rha Sung-Eun
Byun Jae-Young
Kim Sung-Hoon
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Abstract
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Purpose: To compare the diagnostic accuracy of CT or MRI with 18F-FDG PET/CT for the preoperative staging of ovarian cancer.
Materials and Methods: Twenty-eight patients (15-67 years; mean 46 years) with 38 surgically confirmed ovarian cancer lesions (4-30 cm, mean 11.2 cm) underwent CT or MR (CT on 20; MR on 10) and 18F-FDG PET/CT to compare each imaging modality in accordance to the FIGO stage.
Results: The FIGO staging results revealed stage I disease in 11 patients, stage III disease in 14 patients, and stage IV disease in three patients. In total, six of the 38 tumors (16%) showed no evidence of abnormal uptake on the 18F-FDG PET/CT, while one of the 38 tumors (3%) showed no evidence of enhancing on the solid portion for either CT or MRI. The lack of typical advanced stage characteristics of the aforementioned tumors resulted in their stage I disease classification. The CT or MRI staging was correlated with FIGO staging in 21 of the 28 patients (75%), whereas the 18F-FDG PET/CT staging was similarly correlated in 23 of the 28 patients (82%). We found no significant difference in the diagnostic accuracy of CT or MRI versus the 18F-FDG PET/CT in the preoperative staging of ovarian cancer.
Conclusion: Besides CT or MRI, additional 18F-FDG PET/CT imaging is not mandatory for the preoperative staging of ovarian cancer.
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KEYWORD
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Ovarian neoplasms, Neoplasm staging, Tomography, X-ray computed, Magnetic resonance imaging, Positron emission tomography
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